Acid-PEG4-mono-methyl ester

• CAT Number: I016721
• CAS Number: 2028284-75-3
• Molecular Formula: C13H24O8
• Molecular Weight: 308.32
• Purity: ≥95%
• Synonyms: 3-[2-[2-[2-(3-methoxy-3-oxopropoxy)ethoxy]ethoxy]ethoxy]propanoic acid
• InChI: InChI=1S/C13H24O8/c1-17-13(16)3-5-19-7-9-21-11-10-20-8-6-18-4-2-12(14)15/h2-11H2,1H3,(H,14,15)
• InChIKey: MOGNNSWXCSXEEM-UHFFFAOYSA-N
• SMILES: COC(=O)CCOCCOCCOCCOCCC(=O)O

Acid-PEG4-mono-methyl ester(CAT: I016721) is a monofunctional polyethylene glycol (PEG) derivative featuring a terminal carboxylic acid group and a methyl ester end. The carboxylic acid functionality enables coupling to amines and other reactive groups for bioconjugation, drug design, and surface modification. The PEG4 spacer (four ethylene glycol units) enhances water solubility, increases hydrophilicity, and provides flexibility while minimizing steric hindrance in conjugates. The methyl ester terminus offers stability and protection, making this reagent suitable for linker chemistry and controlled PEGylation strategies. Acid-PEG4-mono-methyl ester is widely used in chemical biology, biomaterials, drug delivery systems, and the development of diagnostic or therapeutic conjugates.