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Acemetacin

Acemetacin

  • CAT Number: A000251
  • CAS Number: 53164-05-9
  • Molecular Formula: C21H18ClNO6
  • Molecular Weight: 415.82
  • Purity: ≥95%
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Acemetacin is a non-steroidal anti-inflammatory drug and a glycolic acid ester of indometacin that is a cyclooxygenase inhibitor.<br>Acemetacin is less potent than indomethacin in causing a concentration-related inhibition of PGE accumulation in gastric mucosal incubates. Acemetacin is also less potent than indomethacin in reducing gastric 6-keto-PGF1 alpha and TXB2.<br>Acemetacin induces significantly less gastric and intestinal damage than indomethacin in rats pretreated with inhibitors of COX-2 and NOS, despite markedly suppressing COX activity.

Catalog Number A000251
CAS Number 53164-05-9
Synonyms

K-708

Molecular Formula

C21H18ClNO6

Purity 95%
Target COX
Solubility Soluble in DMSO
Storage 3 years -20C powder

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