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Aceclidine

Aceclidine

  • CAT Number: T000047
  • CAS Number: 6821-59-6
  • Molecular Formula: C9H15NO2 .C7H6O3
  • Purity: ≥95%
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Aceclidine(cas 6821-59-6)&nbsp;is a selective M-AChR agonist with a rigid bicyclic analog of ACh.&nbsp;
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Quinuclidine derivative<!–C<sub>9</sub>H<sub>15</sub>NO<sub>2</sub> .C<sub>7</sub>H<sub>6</sub>O<sub>3</sub>–>, synthetic<br />
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5-10 μg/kg i.v. in cats cause hypotension. 1.5×10-<sup>6</sup> M in cats cause myosis. 3×10-<sup>8</sup> M in isolated rabbit intestine cause contractions.<br />
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It has a good penetration of biological membranes.<br />
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It has a more potent than NMQ-OAc.
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Catalog Number T000047
CAS Number 6821-59-6
Synonyms

DL-3-acetoxyquinuclidine salicylate

Molecular Formula

C9H15NO2 .C7H6O3

Purity 95%
Solubility In water, ethanol
Storage Store at room temperature. Solution for use: dissolve in water: 10-3M (2 mg in 6.51 ml), stable for 1-2 days at 20°C.
Reference

– Mashkovsky et al., <i>Prog. Drug. Res</i>. (1969). 13:294-339<br />
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– Wienstein et al., <i>Molec. Pharmacol</i>. (1975). 11(5):671-689<br />
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– Mashkovsky et al., <i>Khim. Pharm. Zh.</i> (1967) (Russian). (3):3<br />
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– Barlow et al., <i>Molec. Pharmacol</i>. (1975). 11(5):690-693<br />
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