Abamectin

  • CAT Number: I004674
  • CAS Number: 71751-41-2
  • Molecular Formula: C48H72O14
  • Molecular Weight: 873.1
  • Purity: ≥95%
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Abamectin(CAT: I004674) is a widely used insecticide and acaricide derived from the soil bacterium Streptomyces avermitilis. It belongs to the avermectin family of compounds and has broad-spectrum activity against various insects and mites. Abamectin works by interfering with the nervous system of the target pests, leading to paralysis and ultimately their death. It is commonly used in agriculture to control pests on crops such as vegetables, fruits, and ornamental plants. Additionally, it is used in veterinary medicine to treat parasitic infections in livestock. Abamectin has proven to be effective against a range of pests and has been an important tool in integrated pest management strategies.

Catalog Number I004674
CAS Number 71751-41-2
Molecular Formula

C48H72O14

Purity 95%
Target Antibiotic
Solubility 10mM in water
Storage Store at -20°C
IC50 N/A
IUPAC Name (1'R,2R,3S,4'S,6S,8'R,10'E,12'S,13'S,14'E,16'E,20'R,21'R,24'S)-2-[(2S)-butan-2-yl]-21',24'-dihydroxy-12'-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-3,11',13',22'-tetramethylspiro[2,3-dihydropyran-6,6'-3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene]-2'-one
InChI InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12+,27-15+,32-14+/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1
InChIKey RRZXIRBKKLTSOM-XPNPUAGNSA-N
SMILES CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C
Reference

1: Pirsaheb M, Fattahi N, Rahimi R, Sharafi K, Ghaffari HR. Evaluation of abamectin, diazinon and chlorpyrifos pesticide residues in apple product of Mahabad region gardens: Iran in 2014. Food Chem. 2017 Sep 15;231:148-155. doi: 10.1016/j.foodchem.2017.03.120. Epub 2017 Mar 23. PubMed PMID: 28449991.<br />
2: Xu Z, Liu Y, Wei P, Feng K, Niu J, Shen G, Lu W, Xiao W, Wang J, Smagghe GJ, Xu Q, He L. High Gama-Aminobutyric Acid Contents Involved in Abamectin Resistance and Predation, an Interesting Phenomenon in Spider Mites. Front Physiol. 2017 Apr 11;8:216. doi: 10.3389/fphys.2017.00216. eCollection 2017. PubMed PMID: 28443033; PubMed Central PMCID: PMC5387048.<br />
3: Vasconcelos AM, Daam MA, de Resende JC, Casali-Pereira MP, Esp&iacute;ndola EL. Survival and development of bullfrog tadpoles in microcosms treated with abamectin. Ecotoxicology. 2017 Apr 13. doi: 10.1007/s10646-017-1804-5. [Epub ahead of print] PubMed PMID: 28409414.<br />
4: Mossa AH, Abdel Rasoul MA, Mohafrash SM. Lactational exposure to abamectin induced mortality and adverse biochemical and histopathological effects in suckling pups. Environ Sci Pollut Res Int. 2017 Apr;24(11):10150-10165. doi: 10.1007/s11356-017-8600-x. Epub 2017 Mar 3. PubMed PMID: 28258431.<br />
5: Meligi NM, Hassan HF. Protective effects of Eruca sativa (rocket) on abamectin insecticide toxicity in male albino rats. Environ Sci Pollut Res Int. 2017 Apr;24(10):9702-9712. doi: 10.1007/s11356-017-8671-8. Epub 2017 Mar 1. PubMed PMID: 28251533.<br />
6: Wilkes E, McConaghy FF, Thompson RL, Dawson K, Sangster NC, Hughes KJ. Efficacy of a morantel-abamectin combination for the treatment of resistant ascarids in foals. Aust Vet J. 2017 Mar;95(3):85-88. doi: 10.1111/avj.12559. PubMed PMID: 28239856.<br />
7: Shen XM, Zhong R, Xia WK, Wei D, Ding TB, Liao CY, Niu JZ, Dou W, Wang JJ. Identification of responsive proteins in Panonychus citri exposed to abamectin by a proteomic approach. J Proteomics. 2017 Mar 31;158:9-19. doi: 10.1016/j.jprot.2017.01.020. Epub 2017 Feb 20. PubMed PMID: 28219754.

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