CAS No. : 1424799-20-1

Product Details
For research use only. Not Intended for Therapeutic Use!
Cat No:I013048
Molecular Formula:C₂₄H₁₆F₄N₄O₂
Molecular Weight:468.4
Target: Na+/K+ ATPase Parasite
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Cat No:I013048
Cas No:1424799-20-1
IUPAC Name:(3S,4S)-N-(3-cyano-4-fluorophenyl)-1-oxo-3-pyridin-3-yl-2-(2,2,2-trifluoroethyl)-3,4-dihydroisoquinoline-4-carboxamide
(+)-SJ733 is a clinical candidate for malaria which can also inhibit Na+-ATPase PfATP4.
[1]. Jiménez-Díaz MB, et al. (+)-SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance of Plasmodium. Proc Natl Acad Sci U S A. 2014 Dec 16;111(50):E5455-62.
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