VTP-27999 2,2,2-trifluoroacetate


CAS No. : 1013937-63-7

VTP-27999 2,2,2-trifluoroacetate,1013937-63-7
Product Details
For research use only. Not Intended for Therapeutic Use!
Cat No:I000125
Synonyms:methyl N-[2-[(3-chlorophenyl)-[(3R)-1-[[(2S)-2-(methylamino)-3-[(3R)-oxan-3-yl]propyl]carbamoyl]piperidin-3-yl]methoxy]ethyl]carbamate;2,2,2-trifluoroacetic acid
Molecular Formula:C28H42ClF3N4O7
Molecular Weight:639.1
Target:Renin
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Cat No:I000125
Cas No:1013937-63-7
Product-Name:VTP-27999 2,2,2-trifluoroacetate

VTP-27999 2,2,2-trifluoroacetate is an alkyl amine Renin inhibitor; VTP-27999 is useful for Hypertension and End-Organ Diseases.
IC50 value:
Target: Renin


[1]. Lanqi Jia? et al. Discovery of VTP-27999, an Alkyl Amine Renin Inhibitor with Potential for Clinical Utility ACS Med. Chem. Lett., 2011, 2 (10), pp 747-751
[2]. Ishchenko A, Liu Z, Lindblom P, Wu G, Jim KC, Gregg RD, Claremon DA, Singh SB.Structure-based design technology contour and its application to the design of Renin inhibitors.J Chem Inf Model. 2012 Aug 27;52(8):2089-97. Epub 2012 Jul 25.

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