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8-Hydroxy Guanosine

8-Hydroxy Guanosine

  • CAT Number: R000939
  • CAS Number: 3868-31-3
  • Molecular Formula: C10H13N5O6
  • Molecular Weight: 299.243
  • Purity: ≥95%
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8-<wbr></wbr>Hydroxyguanosine is produced by oxidative damage of RNA. It can be measured in cell digests or in biological fluids as a marker of oxidative stress. When 8-<wbr></wbr>hydroxyguanosine (5-<wbr></wbr>8 mM) is added to Friend erythroleukemia cells, it acts as a growth inhibitor in addition to promoting differentiation.

Catalog Number R000939
CAS Number 3868-31-3
Synonyms

2-Amino-9-β-D-ribofuranosyl-purine-6,8(1H,9H)-dione;?8-OHG; 8-Oxo-7,8-dihydroguanosine; 8-Oxoguanosine; NSC 90393;

Molecular Formula

C10H13N5O6

Purity 95%
Storage Room temperature
IUPAC Name 2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3,7-dihydropurine-6,8-dione
InChI InChI=1S/C10H13N5O6/c11-9-13-6-3(7(19)14-9)12-10(20)15(6)8-5(18)4(17)2(1-16)21-8/h2,4-5,8,16-18H,1H2,(H,12,20)(H3,11,13,14,19)/t2-,4-,5-,8-/m1/s1
InChIKey FPGSEBKFEJEOSA-UMMCILCDSA-N
SMILES C(C1C(C(C(O1)N2C3=C(C(=O)N=C(N3)N)NC2=O)O)O)O

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