7-Methylguanosine 5'-diphosphate sodium

• CAT Number: M008741
• CAS Number: 104809-16-7
• Molecular Formula: C11H16N5NaO11P2
• Molecular Weight: 479.21
• Purity: ≥95%
• Synonyms: sodium;[[(2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1H-purin-9-ium-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl] hydrogen phosphate
• IUPAC Name: [(2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1,8-dihydropurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphono hydrogen phosphate
• InChI: InChI=1S/C11H19N5O11P2/c1-15-3-16(8-5(15)9(19)14-11(12)13-8)10-7(18)6(17)4(26-10)2-25-29(23,24)27-28(20,21)22/h4,6-7,10,17-18H,2-3H2,1H3,(H,23,24)(H2,20,21,22)(H3,12,13,14,19)/t4-,6-,7-,10-/m1/s1
• InChIKey: QQODJOAVWUWVHJ-KQYNXXCUSA-N
• SMILES: CN1CN(C2=C1C(=O)NC(=N2)N)[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)OP(=O)(O)O)O)O

7-Methylguanosine 5′-diphosphate sodium（Cat No.:M008741）is a nucleotide analog used in molecular biology and biochemical research to study RNA synthesis, processing, and cap-dependent translation. It mimics the naturally occurring mRNA cap structure, enabling researchers to investigate mRNA stability, ribosome recruitment, and translational regulation. This compound is particularly useful in assays examining the role of cap-binding proteins such as eIF4E. Its sodium salt form enhances solubility for in vitro applications, making it a practical reagent in enzymatic studies, RNA–protein interaction analyses, and the development of therapeutic strategies targeting mRNA translation pathways.