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5(S)-HETE Lipid Maps® MS Standard

5(S)-HETE Lipid Maps® MS Standard

  • CAT Number: R015575
  • CAS Number: 70608-72-9
  • Molecular Formula: C20H32O3
  • Molecular Weight: 320.473
  • Purity: ≥95%
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5(S)-<wbr />HETE (CAS&nbsp;70608-72-9) is produced by the action of 5-<wbr />LO on arachidonic acid to give 5(S)-<wbr />HpETE, followed by reduction of the hydroperoxide. 5(S)-<wbr />HETE has proliferative and chemotactic effects on granulocytes. When further metabolized to 5-<wbr />oxoETE, it is a more potent eosinophil chemoattractant than leukotriene B<sub>4</sub>.

Catalog Number R015575
CAS Number 70608-72-9
Molecular Formula

C20H32O3

Purity 95%
Storage -20°C
IUPAC Name (5S,6E,8Z,11Z,14Z)-5-hydroxyicosa-6,8,11,14-tetraenoic acid
InChI InChI=1S/C20H32O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-19(21)17-15-18-20(22)23/h6-7,9-10,12-14,16,19,21H,2-5,8,11,15,17-18H2,1H3,(H,22,23)/b7-6-,10-9-,13-12-,16-14+/t19-/m1/s1
InChIKey KGIJOOYOSFUGPC-JGKLHWIESA-N
SMILES CCCCCC=CCC=CCC=CC=CC(CCCC(=O)O)O
Reference

1.Dodge, W., and Thomas, M. The effect of 5-hydroxyeicosatetraenoic acid on the proliferation of granulocyte progenitors and embryonic fibroblasts of the chick. Biochemical and Biophysical Research Communications 131, 731-735 (1985).

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