For research use only. Not for therapeutic Use.
4-Phenylbutyric acid (Cat No.:R048396), also known as Benzenebutyric acid, is a histone deacetylase (HDAC) inhibitor that plays a significant role in regulating hepatic hepcidin against HCV (Hepatitis C virus). By inhibiting HDAC, it modulates the acetylation of histones, leading to changes in gene expression and epigenetic regulation. Furthermore, 4-Phenylbutyric acid exhibits anti-inflammatory effects by modulating endoplasmic reticulum (ER) stress and autophagy in an acute lung injury model induced by LPS (lipopolysaccharide). Its diverse properties make it a potential candidate for various therapeutic applications, including hepatic and inflammatory conditions.
| CAS Number | 1821-12-1 |
| Synonyms | Benzenebutanoic Acid; 4-Phenyl-n-butyric Acid; γ-Phenylbutanoic Acid; NSC 295; |
| Molecular Formula | C10H12O2 |
| Purity | ≥95% |
| Target | Epigenetics |
| Storage | RT |
| IUPAC Name | 4-phenylbutanoic acid |
| InChI | InChI=1S/C10H12O2/c11-10(12)8-4-7-9-5-2-1-3-6-9/h1-3,5-6H,4,7-8H2,(H,11,12) |
| InChIKey | OBKXEAXTFZPCHS-UHFFFAOYSA-N |
| SMILES | C1=CC=C(C=C1)CCCC(=O)O |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
