4-Bromo-1H-pyrrolo[2,3-B]pyridine-3-carbaldehyde

• CAT Number: L041189
• CAS Number: 1000340-35-1
• Molecular Formula: C8H5BrN2O
• Molecular Weight: 225.04
• Purity: ≥95%
• IUPAC Name: 4-bromo-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde
• InChI: InChI=1S/C8H5BrN2O/c9-6-1-2-10-8-7(6)5(4-12)3-11-8/h1-4H,(H,10,11)
• InChIKey: GVJOYNDJFISGTG-UHFFFAOYSA-N
• SMILES: C1=CN=C2C(=C1Br)C(=CN2)C=O

4-Bromo-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde(CAT: L041189) is a heteroaromatic compound incorporating both pyrrole and pyridine rings, functionalized with a bromo substituent and an aldehyde group. This dual functionality makes it a highly versatile synthetic intermediate for medicinal and organic chemistry. The bromine atom enables cross-coupling reactions such as Suzuki, Stille, or Buchwald–Hartwig couplings, while the aldehyde group provides a handle for condensation and derivatization reactions. Researchers employ this scaffold in the design of kinase inhibitors, CNS-active compounds, and heterocyclic drug candidates, where fused bicyclic systems are central to biological activity. Its stability and reactivity profile make it a valuable building block in drug discovery and heterocyclic chemistry.