3'-O-tert-Butyldimethylsilyl-5'-O-DMT-N2-isobutyrylguanosine 2'-CE phosphoramidite

• CAT Number: L021339
• CAS Number: 1445905-51-0
• Molecular Formula: C50H68N7O9PSi
• Molecular Weight: 970.2
• Purity: ≥95%
• Storage: 2-8°C
• IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[tert-butyl(dimethyl)silyl]oxy-3-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide
• InChI: InChI=1S/C50H68N7O9PSi/c1-32(2)45(58)54-48-53-44-41(46(59)55-48)52-31-56(44)47-43(65-67(63-29-17-28-51)57(33(3)4)34(5)6)42(66-68(12,13)49(7,8)9)40(64-47)30-62-50(35-18-15-14-16-19-35,36-20-24-38(60-10)25-21-36)37-22-26-39(61-11)27-23-37/h14-16,18-27,31-34,40,42-43,47H,17,29-30H2,1-13H3,(H2,53,54,55,58,59)/t40-,42-,43-,47-,67?/m1/s1
• InChIKey: JCCWPNDXSMAHGZ-FTZVBZPOSA-N
• SMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)O[Si](C)(C)C(C)(C)C)OP(N(C(C)C)C(C)C)OCCC#N

3′-O-tert-Butyldimethylsilyl-5′-O-DMT-N2-isobutyrylguanosine 2′-CE phosphoramidite（Cat No.:L021339）, is a chemical compound used in nucleotide synthesis for oligonucleotide and RNA research. It is a modified guanosine derivative with a test-butyldimethylsilyl group protecting the 3′-hydroxyl, a dimethoxytrityl (DMT) group protecting the 5′-hydroxyl, and an isobutyl group at the N2 position of the guanosine ring. The 2′-CE phosphoramidite moiety allows for efficient coupling during solid-phase DNA synthesis, facilitating the creation of modified oligonucleotides with specific functionalities.