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3'-O-(t-butyldimethylsilyl)thymidine

3'-O-(t-butyldimethylsilyl)thymidine

  • CAT Number: L022145
  • CAS Number: 40733-27-5
  • Molecular Formula: C16H28N2O5Si
  • Molecular Weight: 356.49
  • Purity: ≥95%
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3′-O-(t-butyldimethylsilyl)thymidine (Cat.No:L022145) is a modified nucleoside used in nucleic acid synthesis. Its thymidine base is protected by a t-butyldimethylsilyl group at the 3′ position. This silylation protects the nucleoside during chemical reactions and can be subsequently removed, allowing controlled modification of nucleic acids for research or therapeutic purposes.

Catalog Number L022145
CAS Number 40733-27-5
Molecular Formula

C16H28N2O5Si

Purity 95%
IUPAC Name 1-[(2R,4S,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
InChI InChI=1S/C16H28N2O5Si/c1-10-8-18(15(21)17-14(10)20)13-7-11(12(9-19)22-13)23-24(5,6)16(2,3)4/h8,11-13,19H,7,9H2,1-6H3,(H,17,20,21)/t11-,12+,13+/m0/s1
InChIKey QAPSNMNOIOSXSQ-YNEHKIRRSA-N

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