3-Dehydrotrametenolic acid

  • CAT Number: I018549
  • CAS Number: 29220-16-4
  • Molecular Formula: C₃₀H₄₆O₃
  • Molecular Weight: 454.68
  • Purity: ≥95%
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3-Dehydrotrametenolic acid(Cat No.:I018549), derived from Poria cocos sclerotium, is a lactate dehydrogenase (LDH) inhibitor. In vitro, studies have shown that it promotes adipocyte differentiation and exhibits insulin-sensitizing properties in vivo. Additionally, 3-Dehydrotrametenolic acid induces apoptosis and demonstrates anticancer activity. This compound holds potential for therapeutic applications in diabetes, obesity, and cancer treatment.

Catalog Number I018549
CAS Number 29220-16-4
Molecular Formula

C₃₀H₄₆O₃

Purity 95%
Storage Sealed in dry,Room Temperature
IUPAC Name (2R)-2-[(3S,5R,10S,13R,14R,17R)-3-hydroxy-4,4,10,13,14-pentamethyl-2,3,5,6,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-6-methylhept-5-enoic acid
InChI InChI=1S/C30H46O3/c1-19(2)9-8-10-20(26(32)33)21-13-17-30(7)23-11-12-24-27(3,4)25(31)15-16-28(24,5)22(23)14-18-29(21,30)6/h9,11,14,20-21,24-25,31H,8,10,12-13,15-18H2,1-7H3,(H,32,33)/t20-,21-,24+,25+,28-,29-,30+/m1/s1
InChIKey QFPLAAZRZNKRRY-GIICLEHTSA-N
SMILES CC(=CCCC(C1CCC2(C1(CC=C3C2=CCC4C3(CCC(C4(C)C)O)C)C)C)C(=O)O)C
Reference

[1]. De Nicola GR, et al. Novel gram-scale production of enantiopure R-sulforaphane from Tuscan black kale seeds. Molecules. 2014 May 27;19(6):6975-86.<br>[2]. Abdull Razis AF, et al. The natural chemopreventive phytochemical R-sulforaphane is a far more potent inducer of the carcinogen-detoxifying enzyme systems in rat liver and lung than the S-isomer. Int J Cancer. 2011 Jun 15;128(12):2775-82.

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