For research use only. Not for therapeutic Use.
(2S,5S)-Censavudine（Cat No.:I045064）is a stereoisomer of Censavudine, a nucleoside reverse transcriptase inhibitor (NRTI) designed to target HIV-1 replication. This compound mimics natural nucleosides, becoming incorporated into viral DNA by reverse transcriptase and causing chain termination, effectively inhibiting viral replication. The (2S,5S) configuration reflects its specific chiral centers, which may influence binding affinity and pharmacokinetics. It is particularly valuable in preclinical studies aimed at understanding stereoselective activity, resistance profiles, and toxicity.
| Synonyms | 1-[(2S,5S)-5-ethynyl-5-(hydroxymethyl)-2H-furan-2-yl]-5-methylpyrimidine-2,4-dione |
| Molecular Formula | C12H12N2O4 |
| Purity | ≥95% |
| IUPAC Name | 1-[(2S,5S)-5-ethynyl-5-(hydroxymethyl)-2H-furan-2-yl]-5-methylpyrimidine-2,4-dione |
| InChI | InChI=1S/C12H12N2O4/c1-3-12(7-15)5-4-9(18-12)14-6-8(2)10(16)13-11(14)17/h1,4-6,9,15H,7H2,2H3,(H,13,16,17)/t9-,12+/m0/s1 |
| InChIKey | OSYWBJSVKUFFSU-JOYOIKCWSA-N |
| SMILES | CC1=CN(C(=O)NC1=O)[C@@H]2C=C[C@@](O2)(CO)C#C |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
