(2S,4R)-1-(tert-Butoxycarbonyl)-4-hydroxypiperidine-2-carboxylic acid

• CAT Number: L037345
• CAS Number: 955016-25-8
• Molecular Formula: C11H19NO5
• Molecular Weight: 245.27
• Purity: ≥95%
• IUPAC Name: (2S,4R)-4-hydroxy-1-[(2-methylpropan-2-yl)oxycarbonyl]piperidine-2-carboxylic acid
• InChI: InChI=1S/C11H19NO5/c1-11(2,3)17-10(16)12-5-4-7(13)6-8(12)9(14)15/h7-8,13H,4-6H2,1-3H3,(H,14,15)/t7-,8+/m1/s1
• InChIKey: GCAZZUFIDGXTDA-SFYZADRCSA-N
• SMILES: CC(C)(C)OC(=O)N1CC[C@H](C[C@H]1C(=O)O)O

(2S,4R)-1-(tert-Butoxycarbonyl)-4-hydroxypiperidine-2-carboxylic acid（Cat No.:L037345）is a chiral, bicyclic amino acid derivative featuring a piperidine ring substituted with a hydroxyl group at the 4-position, a carboxylic acid at the 2-position, and a tert-butoxycarbonyl (Boc) group protecting the nitrogen. The (2S,4R) configuration imparts precise stereochemistry, making it valuable in peptidomimetic design and asymmetric synthesis. The hydroxyl and carboxyl groups offer sites for further functionalization or hydrogen bonding. Commonly used in pharmaceutical research, it serves as a versatile building block for bioactive molecules, especially where conformational constraint and stereocontrol are critical.