(2S,3S,5S)-5-Amino-1,6-diphenyl-2-([[thiazol-5-ylmethoxy)carbonyl]amino]hexan-3-yl 2-(3-((2-isopropylthiazol-4-yl)methyl)-3-methylureido)-3-methylbutanoate Hydrochloride

• CAT Number: C000384
• CAS Number: 959315-21-0
• Molecular Formula: C₃₇H₄₈N₆O₅S₂•xHCl
• Purity: ≥95%
• Solubility: DMSO (Slightly), Methanol (Sparingly)
• Storage: -20°C, Hygroscopic

(2S,3S,5S)-5-amino-1,6-diphenyl-2-([[thiazol-5-ylmethoxy)carbonyl]amino]hexan-3-yl 2-(3-((2-isopropylthiazol-4-yl)methyl)-3-methylureido)-3-methylbutanoate Hydrochloride, is a prodrug of Ritonavir , which is a selective HIV protease inhibitor.

Reference

Daluge, S., et al.: Antimicrob. Agents Chemother., 38, 1590 (1994), Ammaranond, P., et al.: J. Clin. Virol., 26, 153 (2003), Harrigan, P., et al.: J. Infect. Dis., 191, 339 (2005), Miller, J., et al.: Bioorg. Med. Chem. Lett., 16, 1788 (2006);