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(2S)-2-Ethyl-8-methyl-1-thia-4,8-diazaspiro[4,5]decan-3-one

(2S)-2-Ethyl-8-methyl-1-thia-4,8-diazaspiro[4,5]decan-3-one

  • CAT Number: R007567
  • CAS Number: 503431-81-0
  • Molecular Formula: C10H18N2OS
  • Molecular Weight: 214.327
  • Purity: ≥95%
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NGX-267 is a muscarinic M1 agonist potentially for the treatment of Xerostomia, Alzheimer/’s disease and cognitive

Catalog Number R007567
CAS Number 503431-81-0
Molecular Formula

C10H18N2OS

Purity 95%
Target muscarinic M1 agonist
Storage Store at -20°C
IUPAC Name (2S)-2-ethyl-8-methyl-1-thia-4,8-diazaspiro[4.5]decan-3-one
InChI InChI=1S/C10H18N2OS/c1-3-8-9(13)11-10(14-8)4-6-12(2)7-5-10/h8H,3-7H2,1-2H3,(H,11,13)/t8-/m0/s1
InChIKey PHOZOHFUXHPOCK-QMMMGPOBSA-N
SMILES CCC1C(=O)NC2(S1)CCN(CC2)C
Reference

</br>1: Heinrich JN, Butera JA, Carrick T, Kramer A, Kowal D, Lock T, Marquis KL,</br> Pausch MH, Popiolek M, Sun SC, Tseng E, Uveges AJ, Mayer SC. Pharmacological</br> comparison of muscarinic ligands: historical versus more recent muscarinic</br> M1-preferring receptor agonists. Eur J Pharmacol. 2009 Mar 1;605(1-3):53-6. doi: </br> 10.1016/j.ejphar.2008.12.044. PubMed PMID: 19168056.</br></br>

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