For research use only. Not for therapeutic Use.
2′,3′-Dideoxy-5-iodouridine(Cat No.:M011682)is a halogenated uridine analog characterized by the absence of hydroxyl groups at the 2′ and 3′ positions and an iodine atom at the 5-position of the uracil ring. This structural modification enhances lipophilicity and resistance to nucleases, making it a valuable tool in antiviral research and nucleic acid chemistry. It is often employed to study nucleoside analog incorporation, viral reverse transcriptase inhibition, and RNA labeling applications. The iodination enables potential radiolabeling for imaging or tracking in biochemical assays and molecular diagnostics.
CAS Number | 105784-83-6 |
Synonyms | 1-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidine-2,4-dione |
Molecular Formula | C9H11IN2O4 |
Purity | ≥95% |
IUPAC Name | 1-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidine-2,4-dione |
InChI | InChI=1S/C9H11IN2O4/c10-6-3-12(9(15)11-8(6)14)7-2-1-5(4-13)16-7/h3,5,7,13H,1-2,4H2,(H,11,14,15)/t5-,7+/m0/s1 |
InChIKey | OBGFSDPYSQAECJ-CAHLUQPWSA-N |
SMILES | C1C[C@@H](O[C@@H]1CO)N2C=C(C(=O)NC2=O)I |
Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |