2,2,2-Trifluoroethyl Triflate

• CAT Number: R053459
• CAS Number: 6226-25-1
• Molecular Formula: C3H2F6O3S
• Molecular Weight: 232.096
• Purity: ≥95%
• Storage: -20°C
• IUPAC Name: 2,2,2-trifluoroethyl trifluoromethanesulfonate
• InChI: InChI=1S/C3H2F6O3S/c4-2(5,6)1-12-13(10,11)3(7,8)9/h1H2
• InChIKey: RTMMSCJWQYWMNK-UHFFFAOYSA-N
• SMILES: C(C(F)(F)F)OS(=O)(=O)C(F)(F)F

2,2,2-Trifluoroethyl Triflate (CAT: R053459) is a chemical compound belonging to the class of triflates, which are compounds containing the trifluoromethanesulfonyl (CF₃SO₂) group. It acts as a versatile electrophilic trifluoromethylating reagent, facilitating the introduction of trifluoromethyl groups into various organic molecules. The compound’s mode of action involves the transfer of the trifluoromethyl group to nucleophilic centers in reactions catalyzed by Lewis acids or bases. This compound finds application as a valuable tool in synthetic organic chemistry, enabling the synthesis of diverse pharmaceuticals, agrochemicals, and materials by incorporating the electron-withdrawing trifluoromethyl moiety into target molecules, thereby modulating their physicochemical and pharmacological properties.