20β-Dihydrocortisol

  • CAT Number: R060042
  • CAS Number: 116-58-5
  • Molecular Formula: C21H32O5
  • Molecular Weight: 364.482
  • Purity: ≥95%
Inquiry Now

<p>
<span style="color:#000000;"><span style="font-size:12px;"><span style="font-family:arial,helvetica,sans-serif;">20&beta;-Dihydrocortisol (CAS&nbsp;116-58-5)&nbsp;could be used as a potential non invasive diagnostic test of transmissible spongiform encephalopaties. 20&beta;-Dihydrocortisol is a metabolite of Cortisol, a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland. Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis; suppress the immune system; and aid in fat, protein and carbohydrate metabolism.</span></span></span></p>

Catalog Number R060042
CAS Number 116-58-5
Synonyms

11β,17,20β,21-Tetrahydroxy-pregn-4-en-3-one; 11β,17,20β,21-Tetrahydroxy-4-pregnen-3-one; 11β,17α,20β,21-Tetrahydroxy-pregn-4-en-3-one; 17-(1,2-Dihydroxyethyl)androsten-3-one-11,17-diol; 20β-Hydroxycortisol; 4-Pregene-11β,17α,20β,21-tetrol-3-one; 4-Pr

Molecular Formula

C21H32O5

Purity 95%
Storage Store at -80C
IUPAC Name (8S,9S,10R,11S,13S,14S,17R)-17-[(1R)-1,2-dihydroxyethyl]-11,17-dihydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
InChI InChI=1S/C21H32O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-18,22,24-26H,3-8,10-11H2,1-2H3/t14-,15-,16-,17+,18+,19-,20-,21-/m0/s1
InChIKey AWWCEQOCFFQUKS-LCGKLAOVSA-N
SMILES CC12CCC(=O)C=C1CCC3C2C(CC4(C3CCC4(C(CO)O)O)C)O
Reference

<p>
<span style="color:#000000;"><span style="font-size:12px;"><span style="font-family:arial,helvetica,sans-serif;">1.Susumu, Miyabo, Kishida Shigeru, and Hisada Tomoichiro. &quot;Metabolism and conjugation of 20&beta;-dihydrocortisol by various dog tissues in vitro.&quot;&nbsp;<i style="font-family: Arial, sans-serif; font-size: 13px;">Journal of steroid biochemistry</i>&nbsp;6.2 (1975): 143-146.<br />
2.Morgan, Ruth, et al. &quot;20 [beta]-Dihydrocortisol; a weak endogenous agonist of the glucocorticoid receptor but a potent agonist of the mineralocorticoid receptor.&quot;&nbsp;<i style="font-family: Arial, sans-serif; font-size: 13px;">Society for Endocrinology BES 2017</i>. Vol. 50. BioScientifica, 2017.</span></span></span></p>

Request a Quote

Contact Us at MuseChem

We are committed to providing you with reliable, cost-effective solutions for your chemical needs, while ensuring your safety and comfort. Our team of experts is always available to answer your questions and help you navigate the complexities of the chemical industry.

Whether you're looking for a specific product or need help with a custom synthesis project, we're here to help you discover a new world of chemical possibilities. Contact us today to learn more about how we can assist you with all of your chemical needs.

Our goal is to make the process of ordering chemicals as seamless and hassle-free as possible. Let us know how we can assist you, and we'll get back to you as soon as possible. We look forward to hearing from you!