20β-Dihydrocortisol

• CAT Number: R060042
• CAS Number: 116-58-5
• Molecular Formula: C21H32O5
• Molecular Weight: 364.48
• Purity: ≥95%
• Synonyms: 11β,17,20β,21-Tetrahydroxy-pregn-4-en-3-one; 11β,17,20β,21-Tetrahydroxy-4-pregnen-3-one; 11β,17α,20β,21-Tetrahydroxy-pregn-4-en-3-one; 17-(1,2-Dihydroxyethyl)androsten-3-one-11,17-diol; 20β-Hydroxycortisol; 4-Pregene-11β,17α,20β,21-tetrol-3-one; 4-Pr
• Storage: Store at -80C
• IUPAC Name: (8S,9S,10R,11S,13S,14S,17R)-17-[(1R)-1,2-dihydroxyethyl]-11,17-dihydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
• InChI: InChI=1S/C21H32O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-18,22,24-26H,3-8,10-11H2,1-2H3/t14-,15-,16-,17+,18+,19-,20-,21-/m0/s1
• InChIKey: AWWCEQOCFFQUKS-LCGKLAOVSA-N
• SMILES: C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2[C@H](C[C@]4([C@H]3CC[C@@]4([C@@H](CO)O)O)C)O

20β-Dihydrocortisol（Cat No.:R060042）is a naturally occurring steroid and metabolite of cortisol, formed through the enzymatic reduction of the 20-keto group to a 20β-hydroxyl group. It retains the core pregnane structure and plays a role in glucocorticoid metabolism. Found in human plasma and urine, 20β-dihydrocortisol is often measured in endocrinological studies to assess adrenal function and steroid metabolism. Although it has lower biological activity compared to cortisol, it contributes to the overall steroid profile. It is primarily studied in the context of stress response, hormone regulation, and diagnostic evaluation of adrenal disorders.