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2'-O-Methyl Guanosine

2'-O-Methyl Guanosine

  • CAT Number: R012659
  • CAS Number: 2140-71-8
  • Molecular Formula: C11H15N5O5
  • Molecular Weight: 297.271
  • Purity: 95%
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2&#39;-O-Methylguanosine(cas 2140-71-8) is a modified nucleoside that is produced in tRNAs by the action of tRNA guanosine-2&rsquo;-O-methyltransferase, using <a href="https://www.musechem.com/product/R065242.html">S-adenosyl-L-methionine (Item Nos.&nbsp; R065242) </a>as a substrate. Through its interaction with other modified nucleosides, 2&#39;-O-methylguanosine is thought to stabilize the structure of the tRNA. 2&#39;-O-Methylguanosine can also be found in rRNA. Normal and modified nucleosides, including 2&#39;-O-methylguanosine, have been shown to be secreted by a natural suppressor cell line and induce apoptosis in K562/Molt4 target cells.

Catalog Number R012659
CAS Number 2140-71-8
Molecular Formula

C11H15N5O5

Purity 95
Storage -20°C
IUPAC Name 2-amino-9-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-3H-purin-6-one
InChI InChI=1S/C11H15N5O5/c1-20-7-6(18)4(2-17)21-10(7)16-3-13-5-8(16)14-11(12)15-9(5)19/h3-4,6-7,10,17-18H,2H2,1H3,(H3,12,14,15,19)/t4-,6-,7-,10-/m1/s1
InChIKey OVYNGSFVYRPRCG-KQYNXXCUSA-N
SMILES COC1C(C(OC1N2C=NC3=C2NC(=NC3=O)N)CO)O

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