2-Methyl-Celecoxib

• CAT Number: C000507
• CAS Number: 170570-09-9
• Molecular Formula: C₁₈H₁₆F₃N₃O₂S
• Molecular Weight: 395.4
• Purity: ≥95%
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• Storage: -20°C, Inert atmosphere

2-Methyl-Celecoxib (CAT: C000507) emerges as an analog of the renowned anti-inflammatory drug Celecoxib. This compound is of interest due to its structural similarity to Celecoxib, which is recognized for its role as a selective inhibitor of cyclooxygenase-2 (COX-2), an enzyme involved in inflammation. The introduction of a methyl group in 2-Methyl-Celecoxib could potentially modulate its pharmacological properties, affecting its binding affinity and interactions. Further research is needed to elucidate the compound’s potential impact on COX-2 inhibition, anti-inflammatory effects, and its potential as a therapeutic agent.

Reference

Simon, L.S., et al.: Arthritis Rheum., 41, 1591 (1998), Silverstein, F.E., et al.: J. Am. Med. Assoc., 284, 1247 (2000), Steinbach, G., et al.: N. Engl. J. Med., 342, 1946 (2000),