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2-Guanidinoethylmercaptosuccinic Acid

2-Guanidinoethylmercaptosuccinic Acid

  • CAT Number: I011528
  • CAS Number: 77482-44-1
  • Molecular Formula: C7H13N3O4S
  • Molecular Weight: 235.258
  • Purity: ≥95%
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2-Guanidinoethylmercaptosuccinic acid(CAT: I011528), also known as MESNA, is a sulfur-containing organic compound used as a chemoprotective agent to reduce the toxicity of certain chemotherapy drugs, particularly ifosfamide, and cyclophosphamide. It works by binding to and detoxifying acrolein, a toxic metabolite produced by these drugs. MESNA is administered intravenously or orally and has been shown to significantly reduce the incidence of urotoxicity and hemorrhagic cystitis associated with these chemotherapy agents. It is also used in the treatment of acetaminophen overdose and other toxicities involving the liver.

Catalog Number I011528
CAS Number 77482-44-1
Molecular Formula

C7H13N3O4S

Purity 95%
Target Carboxypeptidase
Solubility Soluble in DMSO
Storage Store at 4°C
IUPAC Name 2-[2-(diaminomethylideneamino)ethylsulfanyl]butanedioic acid
InChI InChI=1S/C7H13N3O4S/c8-7(9)10-1-2-15-4(6(13)14)3-5(11)12/h4H,1-3H2,(H,11,12)(H,13,14)(H4,8,9,10)
InChIKey VKVCLXDFOQQABP-UHFFFAOYSA-N
SMILES C(CSC(CC(=O)O)C(=O)O)N=C(N)N

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