2-BROMO-5-METHOXYBENZYL BROMIDE 97

• CAT Number: M013173
• CAS Number: 19614-12-1
• Molecular Formula: C8H8Br2O
• Molecular Weight: 279.959
• Purity: ≥95%
• Storage: -20°C
• IUPAC Name: 1-bromo-2-(bromomethyl)-4-methoxybenzene
• InChI: InChI=1S/C8H8Br2O/c1-11-7-2-3-8(10)6(4-7)5-9/h2-4H,5H2,1H3
• InChIKey: MURVUTUZSUEIGI-UHFFFAOYSA-N
• SMILES: COC1=CC(=C(C=C1)Br)CBr

2-BROMO-5-METHOXYBENZYL BROMIDE  97 (CAS 19614-12-1) may be used to synthesize 4-[(2-bromo-5-methoxybe<wbr style="color: rgb(102, 94, 88); font-family: Arial, Helvetica, sans-serif; font-variant-ligatures: normal; orphans: 2; widows: 2;" />nzyl)oxy]-6-methyl-2H-pyran-2-one, 3-(benzylamino)coumarin<wbr style="color: rgb(102, 94, 88); font-family: Arial, Helvetica, sans-serif; font-variant-ligatures: normal; orphans: 2; widows: 2;" />s and 1,3,5-tribenzylated products. 

Reference

1.Majumdar, K. C., S. Chakravorty, and N. De. "Palladium mediated bis-and tris-biaryl Heck coupling for the synthesis of heterocycles." Tetrahedron Letters 49.21 (2008): 3419-3422.
2.Majumdar, Krishna C., et al. "Intramolecular cyclization reaction—Palladium (0)-catalyzed cyclization is more effective than tin hydride mediated reaction." Canadian Journal of Chemistry 86.4 (2008): 325-332.
3.Majumdar, Krishna C., Buddhadeb Chattopadhyay, and Abu Taher. "New efficient synthesis of pyrido [2, 3-c] coumarin derivatives by palladium-catalyzed Heck cyclization." Synthesis 2007.23 (2007): 3647-3652.