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2-[2-(2-Azidoethoxy)ethoxy]ethanamine

2-[2-(2-Azidoethoxy)ethoxy]ethanamine

  • CAT Number: M135413
  • CAS Number: 166388-57-4
  • Molecular Formula: C6H14N4O2
  • Molecular Weight: 174.2
  • Purity: ≥95%
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Azido-PEG2-C2-amine (Cat No.:M135413) is a linker molecule belonging to the polyethylene glycol (PEG) class, commonly used in the synthesis of Proteolysis Targeting Chimeras (PROTACs). It enables the connection of a target protein binder with an E3 ubiquitin ligase binder to facilitate targeted protein degradation. Additionally, Azido-PEG2-C2-amine can serve as a non-cleavable linker in the construction of Antibody-Drug Conjugates (ADCs), linking therapeutic payloads to antibodies for targeted delivery in cancer treatment. The inclusion of two PEG units enhances solubility and reduces immunogenicity.

Catalog Number M135413
CAS Number 166388-57-4
Molecular Formula

C6H14N4O2

Purity 95%
Storage Store at RT
IUPAC Name 2-[2-(2-azidoethoxy)ethoxy]ethanamine
InChI InChI=1S/C6H14N4O2/c7-1-3-11-5-6-12-4-2-9-10-8/h1-7H2
InChIKey ZHWGWSYNZIZTFL-UHFFFAOYSA-N
SMILES C(COCCOCCN=[N+]=[N-])N

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