19(S)-HETE

  • CAT Number: M139119
  • CAS Number: 115461-40-0
  • Molecular Formula: C20H32O3
  • Molecular Weight: 320.473
  • Purity: ≥95%
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19-<wbr></wbr>HETE is one of the major cytochrome P450 (CYP450) metabolites of arachidonic acid that is released from the kidney in response to angiotensin II. When formed by the CYP2E1 isoform, 19-<wbr></wbr>HETE is composed of 70% and 30% of the (S) and (R) stereoisomers, respectively. Both 19(S)-<wbr></wbr> and 19(R)-<wbr></wbr>HETE are potent vasodilators of renal preglomerular vessels. 19(S)-<wbr></wbr>HETE stimulates both renal sodium-<wbr></wbr>potassium ATPase and volume absorption in the rabbit proximal straight tubule.

Catalog Number M139119
CAS Number 115461-40-0
Molecular Formula

C20H32O3

Purity 95%
Storage -20°C
IUPAC Name (5Z,8Z,11Z,14Z,19S)-19-hydroxyicosa-5,8,11,14-tetraenoic acid
InChI InChI=1S/C20H32O3/c1-19(21)17-15-13-11-9-7-5-3-2-4-6-8-10-12-14-16-18-20(22)23/h3-6,9-12,19,21H,2,7-8,13-18H2,1H3,(H,22,23)/b5-3-,6-4-,11-9-,12-10-/t19-/m0/s1
InChIKey XFUXZHQUWPFWPR-DZBJBCEBSA-N
SMILES CC(CCCC=CCC=CCC=CCC=CCCCC(=O)O)O

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