(11b,16a)-9-Chloro-11,17-dihydroxy-16-methyl-pregna-1,4-diene-3,20-dione (Mometasone Impurity M)

• CAT Number: C001096
• CAS Number: 57780-86-6
• Molecular Formula: C₂₂H₂₉ClO₄
• Molecular Weight: 392.92
• Purity: ≥95%
• Solubility: DMSO (Slightly)
• Storage: -20°C, Inert atmosphere
• IUPAC Name: (8S,9R,10S,11S,13S,14S,16R,17R)-17-acetyl-9-chloro-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
• InChI: InChI=1S/C22H29ClO4/c1-12-9-17-16-6-5-14-10-15(25)7-8-19(14,3)21(16,23)18(26)11-20(17,4)22(12,27)13(2)24/h7-8,10,12,16-18,26-27H,5-6,9,11H2,1-4H3/t12-,16+,17+,18+,19+,20+,21+,22+/m1/s1
• InChIKey: PPHLHSSXDSBOAQ-QAHQDLQKSA-N
• SMILES: CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)C)O)C)O)Cl)C

(11beta,16alpha)-9-Chloro-11,17-dihydroxy-16-methyl-pregna-1,4-diene-3,20-dione, also known as Mometasone Impurity M (Cat No.:C001096), is a synthetic corticosteroid compound. It is an impurity of Mometasone, a glucocorticoid used in various topical formulations for its anti-inflammatory and immunosuppressive properties. As an impurity, Mometasone Impurity M may need to be controlled or quantified during the production and quality control of Mometasone-containing products.

Reference

Derendorf, H. et al.: J. Clin. Pharmacol., 42, 383 (2002)