1-Bromo-3,5-dimethoxybenzene

• CAT Number: R015825
• CAS Number: 20469-65-2
• Molecular Formula: C8H9BrO2
• Molecular Weight: 217.06
• Purity: ≥95%
• Synonyms: 1-Bromo-3,5-dimethoxybenzene; 3,5-Dimethoxy-1-bromobenzene; 3,5-Dimethoxybromobenzene; 3,5-Dimethoxyphenyl Bromide; 5-Bromo-1,3-dimethoxybenzene
• Storage: -20°C
• IUPAC Name: 1-bromo-3,5-dimethoxybenzene
• InChI: InChI=1S/C8H9BrO2/c1-10-7-3-6(9)4-8(5-7)11-2/h3-5H,1-2H3
• InChIKey: KRWRFIMBWRVMKE-UHFFFAOYSA-N
• SMILES: COC1=CC(=CC(=C1)Br)OC

1-Bromo-3,5-dimethoxybenzene (Cat No.: R015825) is an aromatic compound featuring a benzene ring substituted with a bromine atom at the 1-position and methoxy groups at the 3 and 5 positions. This compound is commonly used as an intermediate in organic synthesis, particularly in cross-coupling reactions such as Suzuki or Buchwald-Hartwig amination, due to the reactive aryl bromide group. The electron-donating methoxy groups influence the ring’s electronic properties, enhancing its reactivity. It is valuable in the synthesis of pharmaceuticals, agrochemicals, and advanced materials.