1-Bromo-3-phenyl-2-propanone

• CAT Number: R018582
• CAS Number: 20772-12-7
• Molecular Formula: C9H9BrO
• Molecular Weight: 213.074
• Purity: ≥95%
• Synonyms: 1-Bromo-3-phenylacetone; Benzyl Bromomethyl Ketone
• Storage: -20°C
• IUPAC Name: 1-bromo-3-phenylpropan-2-one
• InChI: InChI=1S/C9H9BrO/c10-7-9(11)6-8-4-2-1-3-5-8/h1-5H,6-7H2
• InChIKey: CIFGSVFCDAILNK-UHFFFAOYSA-N
• SMILES: C1=CC=C(C=C1)CC(=O)CBr

Reference

[1]. Rath, J.P., Eipert, M., Kinast, S. and Maier, M.E., 2005.
Synthesis of the tetronate-containing core structure of the antibiotic abyssomicin C.
Abstract: The core structure of abyssomicin C (1) containing an oxabicyclooctanone ring and a tetronate was prepared from the addition product of lithium ethyl propiolate and 4-tert-butyldimethylsilyloxycyclohexanone. Tetronate formation via addition of sodium methanolate followed by hydrolysis gave the hydroxy tetronic acid 27. The spiro compound 27 could be cyclized to the tricyclic ­tetronate 23 by a transannular Mitsunobu lactonization. Alterna­tively, 27 could be prepared from the cyanohydrin cis-19.
Synlett, 2005(02), pp.314-318.