1-Bromo-2-fluoro-2-methylpropane

• CAT Number: R053337
• CAS Number: 19869-78-4
• Molecular Formula: C4H8BrF
• Molecular Weight: 155.01
• Purity: ≥95%
• Storage: Store at -20°C
• IUPAC Name: 1-bromo-2-fluoro-2-methylpropane
• InChI: InChI=1S/C4H8BrF/c1-4(2,6)3-5/h3H2,1-2H3
• InChIKey: LJNXHUCQQXLSHS-UHFFFAOYSA-N
• SMILES: CC(C)(CBr)F

1-Bromo-2-fluoro-2-methylpropane(CAS: 19869-78-4) is a bromofluoroalkyl compound used in the preparation for fluoromethyl amino acids.

Reference

[1]. Moens, M., D’hooghe, M. and De Kimpe, N., 2013. A convenient approach towards the 1-aminomethyl-1-fluorocycloalkane scaffold. Tetrahedron Letters, 54(45), pp.6110-6113.

[2]. Moens, M., 2014. New strategies for the synthesis of fluorinated carbo-and heterocyclic compounds (Doctoral dissertation, Ghent University).

[3]. Moens, M., D’hooghe, M. and De Kimpe, N., 2013. A convenient approach towards the 1-aminomethyl-1-fluorocycloalkane scaffold. Tetrahedron Letters, 54(45), pp.6110-6113.

[4]. Olah, G.A., Welch, J.T., Vankar, Y.D., Nojima, M., Kerekes, I. and Olah, J.A., 1979. Synthetic methods and reactions. 63. Pyridinium poly (hydrogen fluoride)(30% pyridine-70% hydrogen fluoride): a convenient reagent for organic fluorination reactions. The Journal of Organic Chemistry, 44(22), pp.3872-3881.