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Home > Reference Standards> > 1-[5-ETHYL-2-HYDROXY-4-[[6-METHYL-6-(1H-TETRAZOL-5-YL)HEPTYL]OXY]PHENYL]ETHANONE
1-[5-ETHYL-2-HYDROXY-4-[[6-METHYL-6-(1H-TETRAZOL-5-YL)HEPTYL]OXY]PHENYL]ETHANONE

1-[5-ETHYL-2-HYDROXY-4-[[6-METHYL-6-(1H-TETRAZOL-5-YL)HEPTYL]OXY]PHENYL]ETHANONE

  • CAT Number: M017090
  • CAS Number: 117690-79-6
  • Molecular Formula: C19H28N4O3
  • Molecular Weight: 360.458
  • Purity: ≥95%
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LY 255283 is a a specific leukotriene B4 (LTB4) receptor antagonist. It inhibits the production of LTB(4) in human peripheral blood polymorphonuclear leukocytes (PMNL) and in monocytes activated by calcium ionophore A23187.

Catalog Number M017090
CAS Number 117690-79-6
Molecular Formula

C19H28N4O3

Purity 95%
Target Leukotriene Receptor
Solubility Soluble in DMSO > 10 mM
Storage Store at +4C
IUPAC Name 1-[5-ethyl-2-hydroxy-4-[6-methyl-6-(2H-tetrazol-5-yl)heptoxy]phenyl]ethanone
InChI InChI=1S/C19H28N4O3/c1-5-14-11-15(13(2)24)16(25)12-17(14)26-10-8-6-7-9-19(3,4)18-20-22-23-21-18/h11-12,25H,5-10H2,1-4H3,(H,20,21,22,23)
InChIKey WCGXJPFHTHQNJL-UHFFFAOYSA-N
SMILES CCC1=C(C=C(C(=C1)C(=O)C)O)OCCCCCC(C)(C)C2=NNN=N2
Reference

</br>1: Uğur M, Melli M. Inhibitory effect of LY 255283 on the synthesis of leukotriene B(4) and thromboxane A(2) in human peripheral blood polymorphonuclear leukocytes and monocytes. Mediators Inflamm. 1993;2(6):407-9. PubMed PMID: 18475555; PubMed Central PMCID: PMC2365434.</br></br>

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