β-Ketoglutaric Acid

• CAT Number: R021157
• CAS Number: 542-05-2
• Molecular Formula: C5H6O5
• Molecular Weight: 146.10
• Purity: ≥95%
• Synonyms: 3-oxo-Glutaric Acid; β-oxo-Glutaric Acid; 1,3-Dicarboxyacetone; 3-Ketoglutaric Acid; 3-Oxoglutaric Acid; 3-Oxopentanedioic Acid; Acetone-1,3-dicarboxylic Acid; s-Acetonedicarboxylic Acid; ; β-Oxoglutaric Acid
• Target: Endogenous Metabolite
• Storage: -80°C
• IUPAC Name: 3-oxopentanedioic acid
• InChI: InChI=1S/C5H6O5/c6-3(1-4(7)8)2-5(9)10/h1-2H2,(H,7,8)(H,9,10)
• InChIKey: OXTNCQMOKLOUAM-UHFFFAOYSA-N
• SMILES: C(C(=O)CC(=O)O)C(=O)O

β-Ketoglutaric acid(CAT: R021157), also known as α-ketoglutaric acid (AKG), is a key intermediate in the citric acid (Krebs) cycle, playing a central role in cellular energy metabolism. Structurally characterized by a five-carbon dicarboxylic acid with a ketone at the β-position, it functions as a critical substrate for transamination reactions and amino acid biosynthesis. β-Ketoglutaric acid is essential in nitrogen metabolism and serves as a precursor for glutamate and glutamine. In biomedical research, it is studied for its antioxidant properties, anti-aging potential, and role in metabolic regulation. It also finds use in nutritional supplements and biochemical assays related to mitochondrial function.