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α-Zearalenol

α-Zearalenol

  • CAT Number: R011709
  • CAS Number: 36455-72-8
  • Molecular Formula: C18H24O5
  • Molecular Weight: 320.4
  • Purity: ≥95%
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<p>Alpha-Zearalenol is a synthetic derivative of the macrolactone mycotoxin zearalenone, which is also manufactured by Fermentek by the method of fungal fermentation.. Alpha-Zearalenol is estrogenically active and demonstrates induction of premature uterine growth, increase of nuclear estrogen receptor levels, and a five fold increase of ornithine decarboxylase level (ODC). The increase of ODC level was 20-fold more pronounced with Alpha-Zearalenol than zearalenone, and Alpha-Zearalenol demonstrated three times more potent estrogenic activity than zearalenone.</p>

Catalog Number R011709
CAS Number 36455-72-8
Molecular Formula

C18H24O5

Purity 95%
Target Estrogen/progestogen Receptor
Solubility Soluble in DMSO
Storage Store at -20°C
InChIKey FPQFYIAXQDXNOR-QDKLYSGJSA-N
Reference

Identification of the naturally occuring isomer of zearalenol produced by Fusarium roseum /’Gibbosum/’ in rice culture. Hagler W.M. et al. Appl. Environ. Microbiol. 1979, 37, 849.<br/><br/>Binding properties of zearalenone mycotoxins to hepatic estrogen receptors. Powell-Jones, W., et al. Mol. Pharmacol. 1981, 20, 35.<br/><br/>Estrogenic activity of zearalenone and zearalanol in the neonatal rat uterus. Sheehan, D.M. et al. Teratology 1984, 90, 383.</span></p>

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