α-Cholestane

• CAT Number: R055417
• CAS Number: 481-21-0
• Molecular Formula: C27H48
• Molecular Weight: 372.68
• Purity: ≥95%
• Storage: room temp
• IUPAC Name: (5R,8R,9S,10S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene
• InChI: InChI=1S/C27H48/c1-19(2)9-8-10-20(3)23-14-15-24-22-13-12-21-11-6-7-17-26(21,4)25(22)16-18-27(23,24)5/h19-25H,6-18H2,1-5H3/t20-,21-,22+,23-,24+,25+,26+,27-/m1/s1
• InChIKey: XIIAYQZJNBULGD-XWLABEFZSA-N
• SMILES: CC(C)CCCC(C)C1CCC2C1(CCC3C2CCC4C3(CCCC4)C)C

α-Cholestane（Cat No.:R055417）, is a naturally occurring organic compound classified as a triterpene. It is a saturated hydrocarbon and one of the core structures in the biosynthesis of steroids in plants and animals, serving as a precursor to various important steroidal compounds like cholesterol and hormones. Cholestane’s structural simplicity makes it a valuable molecule for studying the biosynthesis of more complex steroids. It plays a fundamental role in the regulation of cellular processes and is essential for the proper functioning of living organisms.

Reference

1. R. Iborra et al. “Advanced Glycation in macrophages induces intracellular accumulation of 7-ketocholesterol and total sterols by decreasing the expressionof ABCA-1 and ABCG-1” Lipids in Health and Disease, vol. 10 pp. 1-7, 20112. R. Ostlund et al. “Phytosterols that are naturally present in commercial corn oil significantly reduce cholesterol absorption in humans” Am J Clin Nutr,Vol. 75(6) pp. 1000-1004, 20023. A. de Jong, J. Plat, R. Mensink “Metabolic effects of plant sterols and stanols (Review)” Journal of Nutritional Biochemistry, Vol. 14:7 pp. 362-369, 2003