For research use only. Not for therapeutic Use.
(±)-Darifenacin（Cat No.:I015572）is a muscarinic acetylcholine receptor antagonist with high selectivity for the M3 subtype, which mediates bladder smooth muscle contraction. By inhibiting M3 receptor activity, it reduces detrusor overactivity, thereby alleviating symptoms of overactive bladder such as urgency, frequency, and urge incontinence. The racemic mixture (±) form includes both enantiomers, though therapeutic formulations typically use the active enantiomer. In pharmacological research, (±)-darifenacin is valuable for studying muscarinic receptor function, subtype selectivity, and the development of targeted therapies for urological disorders and smooth muscle dysfunction.
| CAS Number | 133033-93-9 |
| Synonyms | 2-[1-[2-(2,3-dihydro-1-benzofuran-5-yl)ethyl]pyrrolidin-3-yl]-2,2-diphenylacetamide |
| Molecular Formula | C28H30N2O2 |
| Purity | ≥95% |
| IUPAC Name | 2-[1-[2-(2,3-dihydro-1-benzofuran-5-yl)ethyl]pyrrolidin-3-yl]-2,2-diphenylacetamide |
| InChI | InChI=1S/C28H30N2O2/c29-27(31)28(23-7-3-1-4-8-23,24-9-5-2-6-10-24)25-14-17-30(20-25)16-13-21-11-12-26-22(19-21)15-18-32-26/h1-12,19,25H,13-18,20H2,(H2,29,31) |
| InChIKey | HXGBXQDTNZMWGS-UHFFFAOYSA-N |
| SMILES | C1CN(CC1C(C2=CC=CC=C2)(C3=CC=CC=C3)C(=O)N)CCC4=CC5=C(C=C4)OCC5 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
