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(±)-cis-2-(3,5-Dichlorophenylcarbamoy)cyclohexanecarboxylic Acid

(±)-cis-2-(3,5-Dichlorophenylcarbamoy)cyclohexanecarboxylic Acid

  • CAT Number: R041642
  • CAS Number: 1093757-42-6
  • Molecular Formula: C14H15Cl2NO3
  • Molecular Weight: 316.18
  • Purity: ≥95%
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UV0155041 is a potent, positive allosteric modulator/allosteric agonist at mGlu4 receptors (EC50 = 798 and 693 nM at human and rat mGlu4 receptors respectively).

Catalog Number R041642
CAS Number 1093757-42-6
Molecular Formula

C14H15Cl2NO3

Purity 95%
Target GluR
Solubility Soluble in DMSO > 10 mM
Storage Store at RT
InChI InChI=1S/C14H15Cl2NO3/c15-8-5-9(16)7-10(6-8)17-13(18)11-3-1-2-4-12(11)14(19)20/h5-7,11-12H,1-4H2,(H,17,18)(H,19,20)/t11-,12+/m0/s1
InChIKey VSMUYYFJVFSVCA-NWDGAFQWSA-N
SMILES O=C([C@H]1[C@@H](C(NC2=CC(Cl)=CC(Cl)=C2)=O)CCCC1)O
Reference

</br>1: Niswender CM, Johnson KA, Weaver CD, Jones CK, Xiang Z, Luo Q, Rodriguez AL,</br> Marlo JE, de Paulis T, Thompson AD, Days EL, Nalywajko T, Austin CA, Williams MB,</br> Ayala JE, Williams R, Lindsley CW, Conn PJ. Discovery, characterization, and</br> antiparkinsonian effect of novel positive allosteric modulators of metabotropic</br> glutamate receptor 4. Mol Pharmacol. 2008 Nov;74(5):1345-58. doi:</br> 10.1124/mol.108.049551. PubMed PMID: 18664603; PubMed Central PMCID: PMC2574552.</br>

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