Ubiquitination-IN-1

Ubiquitination-IN-1(CAT: I017528) is a small-molecule inhibitor designed to target the ubiquitin–proteasome system, a critical pathway regulating protein turnover, signal transduction, and cellular homeostasis. By interfering with ubiquitination processes, Ubiquitination-IN-1 modulates the degradation of key regulatory proteins involved in cell cycle progression, apoptosis, and stress responses. This makes it a valuable tool compound for studying ubiquitin-dependent signaling and proteostasis. Preclinical studies indicate its potential role in cancer research, where dysregulated ubiquitination contributes to tumor growth and survival, as well as in neurodegenerative disorders linked to protein aggregation. Ubiquitination-IN-1 provides researchers with a selective approach to dissect ubiquitin-mediated pathways.