Recombinant Human Synaptosomal-Associated Protein 25 (SNAP25) Protein (His)

• Purity: Greater than 90% as determined by SDS-PAGE.
• Host Species: Homo sapiens (Human)
• Accession: P60880
• Gene: SNAP25
• CAT.NO: B000214
• Expression Systems: E.coli
• Product Name: Recombinant Human Synaptosomal-Associated Protein 25 (SNAP25) Protein (His)
• Protein Expression Range: 1-206aa
• Tag: N-6His
• Molecular Mass: 27.3kDa
• Form: Liquid or Lyophilized powder
• Buffer: Liquid form: default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
• Storage: 1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C.

t-SNARE is a protein involved in regulating neurotransmitter release and plays a key role in synaptic function within specific neuronal systems. It associates with proteins that mediate vesicle docking and membrane fusion. Additionally, t-SNARE regulates plasma membrane recycling through interactions with CENPF. In pancreatic beta cells, it modulates the gating properties of the delayed rectifier voltage-dependent potassium channel KCNB1. These functions contribute to its essential role in cellular processes, including synaptic transmission, membrane dynamics, and ion channel regulation.