This protein inhibits primary neurogenesis and may be essential for directing neurons along specific differentiation pathways. It plays a crucial role in the formation of somite boundaries during the segmentation of the paraxial mesoderm, contributing to the proper organization of the developing embryo. By regulating neural differentiation and somite formation, it ensures the correct patterning and development of tissues. Its function is critical in guiding cellular fate decisions during early developmental stages, influencing both neural and mesodermal structures.
Product Name | Recombinant Human Delta-Like Protein 3 (DLL3) Protein (His), Active |
Accession | Q9NYJ7 |
Purity | Greater than 85% as determined by SDS-PAGE. |
Endotoxin | Less than 1.0 EU/ug as determined by LAL method. |
Host Species | Homo sapiens (Human) |
Gene | DLL3 |
Source | Mammalian cell |
Protein Expression Range | 27-492aa |
Tag | C-6His |
Molecular Mass | 51.5 kDa |
Form | Lyophilized powder |
Buffer | Lyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0 |
Storage | 1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
Bioactivity | Active |