For research use only. Not for therapeutic Use.
ZINC05007751 (Cat No.: I038706) is a small-molecule compound identified through virtual screening as a potential inhibitor of protein–protein interactions relevant to cancer signaling. It has been reported to interfere with oncogenic pathways by modulating transcription factor activity and disrupting abnormal cell proliferation signals. Researchers use ZINC05007751 as a chemical probe to investigate cancer biology, drug-target interactions, and lead optimization in medicinal chemistry. Its scaffold offers promise for developing new therapeutic candidates, making it valuable in oncology-focused discovery and structure–activity relationship (SAR) studies.
| CAS Number | 591239-68-8 |
| Synonyms | (5Z)-4-methyl-2,6-dioxo-5-[(5-phenylfuran-2-yl)methylidene]pyridine-3-carbonitrile |
| Molecular Formula | C18H12N2O3 |
| Purity | ≥95% |
| InChI | InChI=1S/C18H12N2O3/c1-11-14(17(21)20-18(22)15(11)10-19)9-13-7-8-16(23-13)12-5-3-2-4-6-12/h2-9H,1H3,(H,20,21,22)/b14-9- |
| InChIKey | SNLNUUWCOAPJED-ZROIWOOFSA-N |
| SMILES | CC1=C(C(=O)NC(=O)C1=CC2=CC=C(O2)C3=CC=CC=C3)C#N |
| Reference | [1]. De Donato M, et al. Identification and antitumor activity of a novel inhibitor of the NIMA-related kinase NEK6. Sci Rep. 2018;8(1):16047. Published 2018 Oct 30. |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
