For research use only. Not for therapeutic Use.
ZCAN262 (CAT: I040210) is a novel AMPA receptor modulator that acts through an allosteric binding site to prevent AMPA-mediated excitotoxicity, a pathological process implicated in various neurodegenerative diseases. By stabilizing receptor conformation and modulating glutamate signaling, ZCAN262 offers neuroprotective effects without directly blocking ion flow. This makes it a promising tool for investigating glutamatergic transmission, synaptic plasticity, and neurotoxicity mechanisms. ZCAN262 is suitable for use in CNS disorder research, including studies on stroke, epilepsy, ALS, and Alzheimer’s disease, where AMPA receptor overactivation contributes to neuronal damage and disease progression.
| Synonyms | 2-[2-[(2,4-difluorophenyl)methyl]-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl]-N,N-dimethylpyrimidine-4-carboxamide |
| Molecular Formula | C19H18F2N6O |
| Purity | ≥95% |
| IUPAC Name | 2-[2-[(2,4-difluorophenyl)methyl]-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl]-N,N-dimethylpyrimidine-4-carboxamide |
| InChI | InChI=1S/C19H18F2N6O/c1-25(2)18(28)16-5-6-22-19(23-16)26-8-13-10-27(24-17(13)11-26)9-12-3-4-14(20)7-15(12)21/h3-7,10H,8-9,11H2,1-2H3 |
| InChIKey | JYKQUGHLYOBLQZ-UHFFFAOYSA-N |
| SMILES | CN(C)C(=O)C1=NC(=NC=C1)N2CC3=CN(N=C3C2)CC4=C(C=C(C=C4)F)F |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
