Zanapezil free base

• CAT Number: M093330
• CAS Number: 142852-50-4
• Molecular Formula: C25H32N2O
• Molecular Weight: 376.53
• Purity: ≥95%
• Synonyms: 3-(1-benzylpiperidin-4-yl)-1-(2,3,4,5-tetrahydro-1H-1-benzazepin-8-yl)propan-1-one
• InChI: InChI=1S/C25H32N2O/c28-25(23-11-10-22-8-4-5-15-26-24(22)18-23)12-9-20-13-16-27(17-14-20)19-21-6-2-1-3-7-21/h1-3,6-7,10-11,18,20,26H,4-5,8-9,12-17,19H2
• InChIKey: PMBLXLOXUGVTGB-UHFFFAOYSA-N
• SMILES: C1CCNC2=C(C1)C=CC(=C2)C(=O)CCC3CCN(CC3)CC4=CC=CC=C4

Zanapezil Free Base（Cat No.:M093330）is a potent, selective acetylcholinesterase inhibitor developed for neurodegenerative research, particularly Alzheimer’s disease. It functions by preventing the breakdown of acetylcholine, a neurotransmitter essential for learning and memory, thereby enhancing cholinergic transmission in the brain. Structurally, it is a free base form, offering improved solubility and formulation flexibility for preclinical research. Its pharmacological profile supports investigations into cognitive function, synaptic plasticity, and neuroprotection. Zanapezil is a valuable tool in screening compounds targeting cholinergic pathways and studying mechanisms underlying cognitive impairment and age-related neuronal decline. Intended for in vitro or animal research only.