Z-Glu(OtBu)-OH

• CAT Number: L023501
• CAS Number: 3886-08-6
• Molecular Formula: C17H23NO6
• Molecular Weight: 337.40
• Purity: ≥95%
• IUPAC Name: (2S)-5-[(2-methylpropan-2-yl)oxy]-5-oxo-2-(phenylmethoxycarbonylamino)pentanoic acid
• InChI: InChI=1S/C17H23NO6/c1-17(2,3)24-14(19)10-9-13(15(20)21)18-16(22)23-11-12-7-5-4-6-8-12/h4-8,13H,9-11H2,1-3H3,(H,18,22)(H,20,21)/t13-/m0/s1
• InChIKey: GLMODRZPPBZPPB-ZDUSSCGKSA-N
• SMILES: CC(C)(C)OC(=O)CC[C@@H](C(=O)O)NC(=O)OCC1=CC=CC=C1

Z-Glu(OtBu)-OH（Cat No.:L023501）is a protected form of the amino acid glutamic acid, widely used in peptide synthesis. The Z (benzyloxycarbonyl) group protects the α-amino group, while the OtBu (tert-butyl ester) protects the γ-carboxyl side chain, leaving the α-carboxylic acid free for coupling. This orthogonal protection allows for selective deprotection and stepwise peptide assembly. Z-Glu(OtBu)-OH is particularly valuable in solid-phase peptide synthesis (SPPS) and in creating modified peptides with controlled structural and functional properties. It offers stability and versatility in constructing complex peptide chains.