Z-FY-CHO

• CAT Number: M036938
• CAS Number: 167498-29-5
• Molecular Formula: C26H26N2O5
• Molecular Weight: 446.50
• Purity: ≥95%
• Synonyms: benzyl N-[(2S)-1-[[(2S)-1-(4-hydroxyphenyl)-3-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
• InChI: InChI=1S/C26H26N2O5/c29-17-22(15-20-11-13-23(30)14-12-20)27-25(31)24(16-19-7-3-1-4-8-19)28-26(32)33-18-21-9-5-2-6-10-21/h1-14,17,22,24,30H,15-16,18H2,(H,27,31)(H,28,32)/t22-,24-/m0/s1
• InChIKey: QVDJMLQSYRSZKC-UPVQGACJSA-N
• SMILES: C1=CC=C(C=C1)C[C@@H](C(=O)N[C@@H](CC2=CC=C(C=C2)O)C=O)NC(=O)OCC3=CC=CC=C3

Z-FY-CHO（Cat No.:M036938）is a potent, selective inhibitor of the proteasome’s chymotrypsin-like activity, commonly used in apoptosis and cancer research. It is a peptide aldehyde composed of benzyloxycarbonyl-phenylalanyl-tyrosine-aldehyde, designed to block proteasomal degradation of intracellular proteins. By inhibiting proteasome function, Z-FY-CHO leads to the accumulation of misfolded or regulatory proteins, triggering cell cycle arrest and apoptosis. This compound is particularly valuable for investigating proteasome-dependent signaling pathways and evaluating targeted therapies in oncology. Z-FY-CHO supports studies focused on protein turnover, stress responses, and the development of proteasome-targeting agents.