(Z)-2,2,2-trifluoro-N'-(piperazin-2-ylidene)acetohydrazide

• CAT Number: L028173
• CAS Number: 849832-73-1
• Molecular Formula: C6H9F3N4O
• Molecular Weight: 210.16
• Purity: ≥95%
• IUPAC Name: 2,2,2-trifluoro-N'-(1,2,3,6-tetrahydropyrazin-5-yl)acetohydrazide
• InChI: InChI=1S/C6H9F3N4O/c7-6(8,9)5(14)13-12-4-3-10-1-2-11-4/h10H,1-3H2,(H,11,12)(H,13,14)
• InChIKey: RKIDLJBEMIARHI-UHFFFAOYSA-N
• SMILES: C1CN=C(CN1)NNC(=O)C(F)(F)F

(Z)-2,2,2-Trifluoro-N’-(piperazin-2-ylidene)acetohydrazide（Cat No.:L028173）is a fluorinated heterocyclic compound featuring a trifluoromethyl group, a hydrazide moiety, and a (Z)-configured piperazinylidene linkage. Its structure combines electron-withdrawing and nitrogen-rich components, making it a valuable scaffold in medicinal and synthetic chemistry. The trifluoromethyl group enhances metabolic stability and bioavailability, while the hydrazide and piperazine functionalities offer hydrogen bonding and coordination potential. This compound is useful in the design of bioactive molecules, such as enzyme inhibitors and CNS-targeted agents, and serves as an intermediate for building complex fluorinated pharmaceuticals and chelating ligands.