(Z)-2-Methoxy-5-(3,4,5-Trimethoxystyryl)Aniline

  • CAT Number: M034142
  • CAS Number: 162705-07-9
  • Molecular Formula: C18H21NO4
  • Molecular Weight: 315.369
  • Purity: ≥95%
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AVE-8063 is an antimitotic agent or microtubule inhibitor with potential anticancer activity.

Catalog Number M034142
CAS Number 162705-07-9
Molecular Formula

C18H21NO4

Purity 95%
Target microtubule inhibitor
Storage Store at +4C
IUPAC Name 2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]aniline
InChI InChI=1S/C18H21NO4/c1-20-15-8-7-12(9-14(15)19)5-6-13-10-16(21-2)18(23-4)17(11-13)22-3/h5-11H,19H2,1-4H3/b6-5-
InChIKey QSAMWSFELUCKOA-WAYWQWQTSA-N
SMILES COC1=C(C=C(C=C1)C=CC2=CC(=C(C(=C2)OC)OC)OC)N
Reference

</br>1: Alvarez R, Alvarez C, Mollinedo F, Sierra BG, Medarde M, Peláez R. Isocombretastatins A: 1,1-diarylethenes as potent inhibitors of tubulin polymerization and cytotoxic compounds. Bioorg Med Chem. 2009 Sep 1;17(17):6422-31. doi: 10.1016/j.bmc.2009.07.012. Epub 2009 Jul 9. PubMed PMID: 19647439.</br>2: Liou JP, Chang JY, Chang CW, Chang CY, Mahindroo N, Kuo FM, Hsieh HP. Synthesis and structure-activity relationships of 3-aminobenzophenones as antimitotic agents. J Med Chem. 2004 May 20;47(11):2897-905. PubMed PMID: 15139768. </br> </br>

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