YNT-185

For research use only. Not for therapeutic Use.

  • CAT Number: I044503
  • CAS Number: 1804978-81-1
  • Molecular Formula: C33H37N5O5S
  • Molecular Weight: 615.74
  • Purity: ≥95%
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YNT-185(Cat No.:I044503)is a selective, small-molecule agonist of the orexin 2 receptor (OX2R), a G protein-coupled receptor involved in regulating wakefulness, arousal, and energy homeostasis. By specifically activating OX2R, YNT-185 promotes wake-promoting signaling pathways in the central nervous system, making it a valuable tool for studying sleep-wake mechanisms and potential treatments for sleep disorders such as narcolepsy. It has demonstrated efficacy in preclinical models by increasing locomotor activity and reducing sleep episodes. YNT-185 contributes to the development of orexin-based therapeutics targeting hypersomnia and related neurological conditions.


CAS Number 1804978-81-1
Synonyms

2-(dimethylamino)-N-[2-[3-[[5-[3-(dimethylcarbamoyl)phenyl]-2-methoxyphenyl]sulfonylamino]anilino]ethyl]benzamide

Molecular Formula C33H37N5O5S
Purity ≥95%
IUPAC Name 2-(dimethylamino)-N-[2-[3-[[5-[3-(dimethylcarbamoyl)phenyl]-2-methoxyphenyl]sulfonylamino]anilino]ethyl]benzamide
InChI InChI=1S/C33H37N5O5S/c1-37(2)29-15-7-6-14-28(29)32(39)35-19-18-34-26-12-9-13-27(22-26)36-44(41,42)31-21-24(16-17-30(31)43-5)23-10-8-11-25(20-23)33(40)38(3)4/h6-17,20-22,34,36H,18-19H2,1-5H3,(H,35,39)
InChIKey BXJSAMKIFDDLGI-UHFFFAOYSA-N
SMILES CN(C)C1=CC=CC=C1C(=O)NCCNC2=CC(=CC=C2)NS(=O)(=O)C3=C(C=CC(=C3)C4=CC(=CC=C4)C(=O)N(C)C)OC
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