For research use only. Not for therapeutic Use.
YM511（Cat No.:M135412）is a potent, nonsteroidal aromatase inhibitor that blocks the conversion of androgens to estrogens by inhibiting the aromatase enzyme (CYP19A1). By reducing estrogen biosynthesis, YM511 is used to study hormone-dependent cancers, particularly estrogen receptor-positive breast cancer. It exhibits high specificity and efficacy in suppressing estrogen levels without significantly affecting other steroidogenic pathways. YM511 is valuable in preclinical research for evaluating the role of estrogen in tumor progression and for developing therapies targeting estrogen-driven malignancies. It also aids in exploring endocrine regulation in reproductive and metabolic disorders.
| CAS Number | 148869-05-0 |
| Synonyms | 4-[(4-bromophenyl)methyl-(1,2,4-triazol-4-yl)amino]benzonitrile |
| Molecular Formula | C16H12BrN5 |
| Purity | ≥95% |
| IUPAC Name | 4-[(4-bromophenyl)methyl-(1,2,4-triazol-4-yl)amino]benzonitrile |
| InChI | InChI=1S/C16H12BrN5/c17-15-5-1-14(2-6-15)10-22(21-11-19-20-12-21)16-7-3-13(9-18)4-8-16/h1-8,11-12H,10H2 |
| InChIKey | GGPPBTSXFROGAE-UHFFFAOYSA-N |
| SMILES | C1=CC(=CC=C1CN(C2=CC=C(C=C2)C#N)N3C=NN=C3)Br |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
