For research use only. Not for therapeutic Use.
Yadanziolide A（Cat No.:R066423）is a sesquiterpene lactone isolated from Brucea javanica and related medicinal plants, traditionally used in Asian herbal medicine. Structurally, it belongs to the quassinoid-related lactones, characterized by a lactone ring system that contributes to its potent bioactivity. Research indicates Yadanziolide A exhibits strong cytotoxic, anti-inflammatory, and antimalarial effects, with notable potential in cancer therapy studies. It acts by modulating cellular signaling pathways and inducing apoptosis in tumor cells. These properties make Yadanziolide A an important compound for pharmacological, natural product, and biomedical research.
| CAS Number | 95258-14-3 |
| Synonyms | (1R,2R,3R,6R,8S,12S,13S,14R,15R,16S,17R)-2,3,12,15,16-pentahydroxy-17-(hydroxymethyl)-9,13-dimethyl-5,18-dioxapentacyclo[12.5.0.01,6.02,17.08,13]nonadec-9-ene-4,11-dione |
| Molecular Formula | C20H26O10 |
| Purity | ≥95% |
| IUPAC Name | (1R,2R,3R,6R,8S,12S,13S,14R,15R,16S,17R)-2,3,12,15,16-pentahydroxy-17-(hydroxymethyl)-9,13-dimethyl-5,18-dioxapentacyclo[12.5.0.01,6.02,17.08,13]nonadec-9-ene-4,11-dione |
| InChI | InChI=1S/C20H26O10/c1-7-3-9(22)13(24)17(2)8(7)4-10-18-6-29-19(5-21,14(25)11(23)12(17)18)20(18,28)15(26)16(27)30-10/h3,8,10-15,21,23-26,28H,4-6H2,1-2H3/t8-,10+,11+,12+,13+,14-,15-,17-,18+,19+,20-/m0/s1 |
| InChIKey | QXKKRGMRXXMDDP-JVDXBALSSA-N |
| SMILES | CC1=CC(=O)[C@H]([C@]2([C@H]1C[C@@H]3[C@]45[C@@H]2[C@H]([C@@H]([C@]([C@@]4([C@H](C(=O)O3)O)O)(OC5)CO)O)O)C)O |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
